Peroxisome proliferator‐activated receptor gamma (PPARγ) is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic target
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چکیده
The authors of the above research article have informed the journal that although the paper uses the official nomenclature PPARG to signify the peroxisome proliferator-activated receptor gamma gene, the most prevalent term used in the literature is PPARc. Therefore, the title, abstract, and keywords have been changed and now apply the latter term to improve searchability. The authors apologize for any inconvenience caused.
منابع مشابه
اثرایمونوتراپیوتیک آل- ترانس رتینوئیک اسید بر دیابت تیپ 1 در موش و تاثیر آن بر بیان ژن (peroxisome proliferator- activated receptor gamma (PPARγ
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متن کاملPPARG is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic target
Angiomyolipoma (AML), the most common benign renal tumor, can result in severe morbidity from hemorrhage and renal failure. While mTORC1 activation is involved in its growth, mTORC1 inhibitors fail to eradicate AML, highlighting the need for new therapies. Moreover, the identity of the AML cell of origin is obscure. AML research, however, is hampered by the lack of in vivo models. Here, we esta...
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